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Anti-CD253 Antibody

品牌：Antibodies

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规格：50µl

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Anti-CD253 Antibody

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Name:	Anti-CD253 Antibody See all CD253 primary antibodies
Description:	Rabbit polyclonal antibody to CD253
Specificity:	The antibody detects endogenous levels of total CD253 protein.
Applications:	WB, IF
Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human CD253.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20˚C

Function:	Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Tissue Specificity:	Widespread; most predominant in spleen, lung and prostate.
Sequence Similarities:	Belongs to the tumor necrosis factor family.
Post-Translational Modification:	Tyrosine phosphorylated by PKDCC/VLK.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 8743 Human Omim: 603598 Human SwissProt: P50591 Human Unigene: 478275 Human
Synonyms:	Apo 2 ligand Antibody APO 2L Antibody Apo-2 ligand Antibody Apo-2L Antibody APO2L Antibody CD253 Antibody CD253 antigen Antibody Chemokine tumor necrosis factor ligand superfamily member 10 Antibody Protein TRAIL Antibody TL2 Antibody TNF Related Apoptosis Inducing Ligand Antibody TNF related apoptosis inducing ligand TRAIL Antibody TNF-related apoptosis-inducing ligand Antibody TNF10_HUMAN Antibody TNFSF10 Antibody TRAIL Antibody Tumor necrosis factor (ligand) family member 10 Antibody Tumor Necrosis Factor (ligand) Superfamily Member 10 Antibody Tumor necrosis factor apoptosis inducing ligand splice variant delta Antibody Tumor necrosis factor ligand superfamily member 10 Antibody
Information:	Target information shown above is from the UniProt Consortium.