Anti-CD229 Antibody |产品详情|进口试剂采购网

您好，欢迎来到拜力生物网站！请登录注册

我的订单 | 联系我们 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA试剂盒、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口试剂、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于我们

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-CD229 Antibody

品牌：Antibodies

货号：

规格：100T

货期：

应用：

咨询客服

立即购买加入购物车

Anti-CD229 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-CD229 Antibody See all CD229 primary antibodies
Description:	Mouse monoclonal (HLy9.25) antibody to CD229 (APC).
Specificity:	The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
Applications:	FC, IP, WB, ICC, FUNC
Reactivity:	Human
Immunogen:	CD299-transfected 300.19 pre-B cell line.
Host:	Mouse
Clonality:	Monoclonal
Clone:	HLy9.25
Isotype:	IgG1
Conjugate:	APC
Purification:	Size exclusion chromatography.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline with 15mM Sodium Azide.
Storage:	Store in the dark at 2-8°C. Avoid prolonged exposure to light.

Target

Function:	Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction. Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to increased IL-17 secretion; the costimulatory activity requires SH2D1A (PubMed:22184727). Promotes recruitment of RORC to the IL-17 promoter (PubMed:22989874). May be involved in the maintenance of peripheral cell tolerance by serving as a negative regulator of the immune response. May disable autoantibody responses and inhibit IFN-gamma secretion by CD4(+) T-cells. May negatively regulate the size of thymic innate CD8(+) T-cells and the development of invariant natural killer T (iNKT) cells (By similarity).
Tissue Specificity:	Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.
Cellular Location:	Membrane. Cell membrane.
Database Links:	Entrez Gene: 4063 Human Omim: 600684 Human SwissProt: Q9HBG7 Human Unigene: 403857 Human
Synonyms:	CD229 Antibody Cell surface molecule Ly-9 Antibody Cell surface molecule Ly9 Antibody hly9 Antibody LY 9 Antibody Ly9 Antibody LY9_HUMAN Antibody Lymphocyte antigen 9 Antibody mLY9 Antibody Signaling lymphocytic activation molecule 3 Antibody SLAM family member 3 Antibody SLAMF3 Antibody T lymphocyte surface antigen Ly9 precursor Antibody T-lymphocyte surface antigen Ly-9 Antibody
Information:	Target information shown above is from the UniProt Consortium.