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Anti-CD21 Antibody

品牌：Antibodies

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规格：50µl

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Anti-CD21 Antibody

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Overview

Name:	Anti-CD21 Antibody See all CD21 primary antibodies
Description:	Rabbit polyclonal antibody to CD21
Specificity:	CD21 Polyclonal Antibody detects endogenous levels of CD21 protein.
Applications:	WB, ELISA
Reactivity:	Human
Immunogen:	Synthesized peptide derived from the Internal region of human CD21.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1mg / ml
Formulation:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:	Store at -20˚C / 1 year

Target

Function:	Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
Tissue Specificity:	Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
Involvement in Disease:	Systemic lupus erythematosus 9: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. Immunodeficiency, common variable, 7: A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.
Sequence Similarities:	Belongs to the receptors of complement activation (RCA) family.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 1380 Human Omim: 120650 Human SwissProt: P20023 Human Unigene: 445757 Human
Synonyms:	C3DR Antibody CD 21 Antibody CD21 Antibody Complement C3d receptor Antibody Complement C3d receptor 2 Antibody Complement component (3d/Epstein Barr virus) receptor 2 Antibody Complement receptor type 2 Antibody CR Antibody Cr2 Antibody CR2_HUMAN Antibody CVID7 Antibody EBV receptor Antibody EBV-R Antibody Epstein Barr virus receptor Antibody Epstein-Barr virus receptor Antibody EVBR Antibody SLEB9 Antibody
Information:	Target information shown above is from the UniProt Consortium.