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Anti-CD101 Antibody

品牌：Antibodies

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规格：50µl

货期：

应用：

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Anti-CD101 Antibody

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Overview

Name:	Anti-CD101 Antibody See all CD101 primary antibodies
Description:	Rabbit polyclonal antibody to CD101
Specificity:	CD101 Polyclonal Antibody detects endogenous levels of CD101 protein.
Applications:	WB, ELISA
Reactivity:	Human
Immunogen:	Synthesized peptide derived from the Internal region of human CD101.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1mg / ml
Formulation:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:	Store at -20˚C / 1 year

Target

Function:	Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.
Tissue Specificity:	Expressed in lung, thymus and small intestine. Detected in cutaneous dendritic cells, activated T-cells, monocytes and granulocytes as well as with epithelial cells with dendritic morphology. Expressed in some leukemic cells, the CD4(+) CD56(+) blastic tumor cells, as well as in Langerhans cells from LCH (Langerhans cell histiocytosis) patients.
Post-Translational Modification:	N-glycosylated.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 9398 Human Omim: 604516 Human SwissProt: Q93033 Human Unigene: 654598 Human Unigene: 74115 Human
Synonyms:	CD101 Antibody CD101 molecule Antibody cell surface glycoprotein V7 Antibody EWI-101 Antibody glu-Trp-Ile EWI motif-containing protein 101 Antibody IGSF2 Antibody Immunoglobulin superfamily member 2 Antibody Leukocyte surface protein Antibody V7 Antibody V7 LSB Antibody
Information:	Target information shown above is from the UniProt Consortium.