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Anti-CCL4 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CCL4 Antibody

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Overview

Name:	Anti-CCL4 Antibody See all CCL4 primary antibodies
Description:	Rabbit polyclonal antibody to CCL4
Specificity:	The antibody detects endogenous levels of total CCL4 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human chemokine (C-C motif) ligand 4
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2.3mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
Sequence Similarities:	Belongs to the intercrine beta (chemokine CC) family.
Post-Translational Modification:	N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes.
Cellular Location:	Secreted.
Database Links:	Entrez Gene: 388372?Human Entrez Gene: 6351?Human Entrez Gene: 9560?Human Omim: 182284?Human Omim: 603782?Human Omim: 610757?Human SwissProt: P13236?Human SwissProt: Q8NHW4?Human Unigene: 655293?Human Unigene: 661942?Human Unigene: 75703?Human
Synonyms:	MIP 1 beta Antibody Secreted protein G 26 Antibody ACT 2 Antibody ACT-2 Antibody ACT2 Antibody AT744.1 Antibody AT744.2 Antibody C C motif chemokine 4 Antibody C C motif chemokine 4 like Antibody C C motif chemokine ligand 4 like 1 Antibody C C motif chemokine ligand 4 like 2 Antibody CC chemokine ligand 4 Antibody CC chemokine ligand 4L1 Antibody CC chemokine ligand 4L1d2 Antibody CC chemokine ligand 4L2 Antibody CCL4 Antibody CCL4L Antibody ccl4l 1 Antibody CCL4L1 Antibody CCL4_HUMAN Antibody Chemokine (C C motif) ligand 4 Antibody Chemokine (C C motif) ligand 4 like 1 Antibody Chemokine (C C motif) ligand 4 like 1, telomeric Antibody Chemokine (C C motif) ligand 4 like 2 Antibody Chemokine CC Motif Ligand 4 Antibody G 26 Antibody G 26 T lymphocyte secreted protein Antibody G-26 T-lymphocyte-secreted protein Antibody HC21 Antibody Immune activation 2 Antibody LAG 1 Antibody LAG-1 Antibody LAG1 Antibody Lymphocyte activation gene 1 Antibody Lymphocyte activation gene 1 protein Antibody Macrophage Inflammatory Protein 1 beta Antibody Macrophage inflammatory protein 1-beta Antibody Macrophage inflammatory protein 1b2 Antibody MGC104418 Antibody MGC126025 Antibody MGC126026 Antibody MIP-1-beta Antibody MIP-1-beta(1-69) Antibody MIP-1-beta(3-69) Antibody MIP1 beta Antibody MIP1B Antibody MIP1B1 Antibody Monocyte adherence induced protein 5 alpha Antibody PAT 744 Antibody Protein H400 Antibody SCYA2 Antibody SCYA4 Antibody SCYA4L Antibody SCYA4L1 Antibody SCYA4L2 Antibody SCYQ4L2 Antibody Secreted protein G 26 Antibody Secreted protein G26 Antibody SIS gamma Antibody SIS-gamma Antibody Small inducible cytokine A4 Antibody Small inducible cytokine A4 (homologous to mouse Mip 1b) Antibody small inducible cytokine A4-like Antibody Small-inducible cytokine A4 Antibody T cell activation protein 2 Antibody T-cell activation protein 2 Antibody
Information:	Target information shown above is from the UniProt Consortium.