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Anti-CCL22 Antibody

品牌：Antibodies

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规格：50µl

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Anti-CCL22 Antibody

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Overview

Name:	Anti-CCL22 Antibody See all CCL22 primary antibodies
Description:	Rabbit polyclonal antibody to CCL22.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:100.
Reactivity:	Human, Rat
Immunogen:	Recombinant protein of human CCL22.
Protein Length:	93
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
Tissue Specificity:	Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis.
Sequence Similarities:	Belongs to the intercrine beta (chemokine CC) family.
Post-Translational Modification:	The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.
Cellular Location:	Secreted.
Database Links:	Entrez Gene: 6367?Human Entrez Gene: 117551?Rat Omim: 602957?Human SwissProt: O00626?Human Unigene: 534347?Human Unigene: 48727?Rat
Synonyms:	A 152E5.1 Antibody A-152E5.1 Antibody ABCD 1 Antibody ABCD1 Antibody C C motif chemokine 22 Antibody C-C motif chemokine 22 Antibody CC chemokine STCP 1 Antibody CC chemokine STCP-1 Antibody ccl 22 Antibody Ccl22 Antibody CCL22_HUMAN Antibody Chemokine (C C motif) ligand 22 Antibody Chemokine (C-C motif) ligand 22 Antibody DC/B CK Antibody DC/B-CK Antibody DCBCK Antibody Macrophage-derived chemokine Antibody MDC Antibody MDC(1-69) Antibody MDC(7-69) Antibody MGC34554 Antibody SCYA22 Antibody Small inducible cytokine A22 Antibody Small inducible cytokine subfamily A (Cys Cys) member 22 Antibody Small inducible cytokine subfamily A (Cys-Cys), member 22 Antibody Small inducible cytokine subfamily A, member 22 Antibody Small-inducible cytokine A22 Antibody STCP 1 Antibody STCP1 Antibody Stimulated T cell chemotactic protein 1 Antibody Stimulated T-cell chemotactic protein 1 Antibody
Information:	Target information shown above is from the UniProt Consortium.