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Anti-CBR1 Antibody

品牌：Antibodies

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规格：50µl

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Anti-CBR1 Antibody

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Name:	Anti-CBR1 Antibody See all CBR1 primary antibodies
Description:	Rabbit polyclonal antibody to CBR1
Specificity:	The antibody detects endogenous levels of total CBR1 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human CBR1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Function:	NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
Sequence Similarities:	Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Cellular Location:	Cytoplasm.
Database Links:	Entrez Gene: 873?Human Omim: 114830?Human SwissProt: P16152?Human Unigene: 606200?Human Unigene: 88778?Human
Synonyms:	15 hydroxyprostaglandin dehydrogenase [NADP+] Antibody 15-hydroxyprostaglandin dehydrogenase [NADP+] Antibody Carbonyl Reductase 1 Antibody Carbonyl reductase [NADPH] 1 Antibody CBR 1 Antibody CBR1 Antibody CBR1_HUMAN Antibody CRN Antibody NADPH dependent carbonyl reductase 1 Antibody NADPH-dependent carbonyl reductase 1 Antibody Prostaglandin 9 ketoreductase Antibody Prostaglandin 9-ketoreductase Antibody Prostaglandin E(2) 9 reductase Antibody Prostaglandin-E(2) 9-reductase Antibody SDR21C1 Antibody
Information:	Target information shown above is from the UniProt Consortium.