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Anti-Cathepsin B (N217) Antibody

品牌：Antibodies

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规格：50µl

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Anti-Cathepsin B (N217) Antibody

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Name:	Anti-Cathepsin B (N217) Antibody See all Cathepsin B primary antibodies
Description:	Rabbit polyclonal antibody to Cathepsin B (N217)
Specificity:	Cathepsin B (N217) pAb detects endogenous levels of Cathepsin B protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 181-230 of Human Cathepsin B.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 36 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Sequence Similarities:	Belongs to the peptidase C1 family.
Cellular Location:	Lysosome. Melanosome. Secreted > Extracellular space. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Database Links:	Entrez Gene: 1508?Human Entrez Gene: 13030?Mouse Entrez Gene: 64529?Rat Omim: 116810?Human SwissProt: P07858?Human SwissProt: P10605?Mouse SwissProt: P00787?Rat Unigene: 520898?Human Unigene: 236553?Mouse Unigene: 472420?Mouse Unigene: 100909?Rat
Synonyms:	Amyloid precursor protein secretase Antibody APP secretase Antibody APPS Antibody CATB_HUMAN Antibody Cathepsin B Antibody Cathepsin B heavy chain Antibody Cathepsin B1 Antibody CathepsinB Antibody CPSB Antibody CTSB Antibody cysteine protease Antibody OTTHUMP00000116009 Antibody OTTHUMP00000229510 Antibody OTTHUMP00000229511 Antibody OTTHUMP00000229512 Antibody OTTHUMP00000229514 Antibody OTTHUMP00000229515 Antibody OTTHUMP00000229516 Antibody Preprocathepsin B Antibody
Information:	Target information shown above is from the UniProt Consortium.