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Anti-caspase 1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-caspase 1 Antibody

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Name:	Anti-caspase 1 Antibody See all caspase 1 primary antibodies
Description:	Rabbit polyclonal antibody to caspase 1
Applications:	ELISA, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide conjugated to KLH
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity purified
Concentration:	1.0mg / ml
Formulation:	PBS, pH 7.4 with 0.02% Sodium Azide
Storage:	This product is stable for several weeks at 4?C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20?C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Function:	Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Tissue Specificity:	Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.
Sequence Similarities:	Belongs to the peptidase C14A family.
Post-Translational Modification:	The two subunits are derived from the precursor sequence by an autocatalytic mechanism.
Cellular Location:	Cytoplasm.
Database Links:	Entrez Gene: 834?Human Omim: 147678?Human SwissProt: P29466?Human Unigene: 2490?Human
Synonyms:	CASP1 Antibody CASP1 nirs variant 1 Antibody Caspase 1 Antibody Caspase 1 apoptosis related cysteine peptidase Antibody caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) Antibody ICE Antibody ICE-like protease Antibody IL1 B convertase Antibody IL1 beta converting enzyme Antibody IL1BC Antibody IL1BCE Antibody Interleukin 1 B converting enzyme Antibody Interleukin 1 beta convertase Antibody P45 Antibody
Information:	Target information shown above is from the UniProt Consortium.