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Anti-CASP2 Antibody

品牌：Antibodies

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规格：50µl

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Anti-CASP2 Antibody

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Name:	Anti-CASP2 Antibody See all CASP2 primary antibodies
Description:	Rabbit polyclonal antibody to CASP2.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human CASP2.
Protein Length:	452
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
Tissue Specificity:	Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In *****s, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Sequence Similarities:	Belongs to the peptidase C14A family.
Post-Translational Modification:	The mature protease can process its own propeptide, but not that of other caspases.