Anti-CaMKII (Ab-286) Antibody |产品详情|进口试剂采购网

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Anti-CaMKII (Ab-286) Antibody

品牌：Antibodies

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规格：50µl

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Anti-CaMKII (Ab-286) Antibody

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Overview

Name:	Anti-CaMKII (Ab-286) Antibody See all CaMKII primary antibodies
Description:	Rabbit polyclonal antibody to CaMKII (Ab-286)
Specificity:	The antibody detects endogenous level of total CaMKII protein.
Applications:	WB, IF
Dilutions:	Western blotting: 1:500~1:1000 Immunofluorescence: 1:100~1:200
Reactivity:	Human, Mouse, Rat
Immunogen:	Peptide sequence around aa.284~288 (Q-E-T-V-D) derived from Human CaMKII.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration:	1.0mg / ml
Predicted MW:	50kd
Formulation:	Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target

Function:	CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).
Sequence Similarities:	Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Cellular Location:	Cell junction > Synapse > Presynaptic cell membrane. Cell junction > Synapse. Postsynaptic lipid rafts.
Database Links:	Entrez Gene: 815 Human Entrez Gene: 816 Human Entrez Gene: 817 Human Entrez Gene: 818 Human Entrez Gene: 108058 Mouse Entrez Gene: 12322 Mouse Entrez Gene: 12323 Mouse Entrez Gene: 12325 Mouse Entrez Gene: 171140 Rat Entrez Gene: 24245 Rat Entrez Gene: 24246 Rat Entrez Gene: 25400 Rat Omim: 114078 Human SwissProt: Q13554 Human SwissProt: Q13555 Human SwissProt: Q13557 Human SwissProt: Q9UQM7 Human SwissProt: P11798 Mouse SwissProt: P28652 Mouse SwissProt: Q6PHZ2 Mouse SwissProt: Q923T9 Mouse SwissProt: P08413 Rat SwissProt: P11275 Rat SwissProt: P11730 Rat SwissProt: P15791 Rat Unigene: 725992 Human Unigene: 131530 Mouse Unigene: 107499 Rat
Synonyms:	Calcium/calmodulin dependent protein kinase II alpha Antibody Calcium/calmodulin dependent protein kinase II beta Antibody Calcium/calmodulin dependent protein kinase II delta Antibody Calcium/calmodulin dependent protein kinase II gamma Antibody Calcium/calmodulin-dependent protein kinase type II subunit alpha Antibody CaM kinase II Antibody CaM kinase II alpha Antibody CaM kinase II beta Antibody CaM kinase II delta Antibody CaM kinase II gamma Antibody CaM kinase II subunit alpha Antibody CaMK-II subunit alpha Antibody CAMK2 Antibody Camk2a Antibody CAMK2B Antibody CAMK2D Antibody CAMK2G Antibody CAMKA Antibody CaMKII Antibody KCC2A_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.