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Anti-BTG2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-BTG2 Antibody

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Name:	Anti-BTG2 Antibody See all BTG2 primary antibodies
Description:	Rabbit polyclonal antibody to BTG2
Specificity:	The antibody detects endogenous levels of total BTG2 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human BTG family, member 2
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.1mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.
Sequence Similarities:	Belongs to the BTG family.
Post-Translational Modification:	Phosphorylated at Ser-147 by MAPK1/ERK2 and MAPK3/ERK1, and at Ser-149 by MAPK14, leading to PIN1-binding and mitochondrial depolarization.
Database Links:	Entrez Gene: 7832?Human Omim: 601597?Human SwissProt: P78543?Human Unigene: 519162?Human
Synonyms:	B cell translocation gene 2 Antibody BTG family member 2 Antibody BTG2 Antibody BTG2_HUMAN Antibody Nerve growth factor inducible anti proliferative Antibody NGF inducible anti proliferative protein PC3 Antibody NGF-inducible anti-proliferative protein PC3 Antibody PC3 Antibody Pheochromacytoma cell 3 Antibody Protein BTG2 Antibody TIS21 Antibody
Information:	Target information shown above is from the UniProt Consortium.