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Anti-BiP / GRP78 (C-term) Antibody

品牌：Antibodies

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规格：50µl

货期：

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Anti-BiP / GRP78 (C-term) Antibody

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Name:	Anti-BiP / GRP78 (C-term) Antibody See all BiP primary antibodies
Description:	Mouse monoclonal antibody to BiP / GRP78 (C-term)
Applications:	WB, ICC
Dilutions:	Western blotting: 1:1000
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant fragment, corresponding to amino acids 487aa-638aa of human HSPA5(C-terminus)
Host:	Mouse
Clonality:	Monoclonal
Isotype:	IgG1
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Predicted MW:	89kd
Formulation:	Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:	store at -20˚C

Function:	Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
Sequence Similarities:	Belongs to the heat shock protein 70 family.
Cellular Location:	Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.