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Anti-BCL3 Antibody

品牌：Antibodies

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规格：100µl

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Anti-BCL3 Antibody

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Name:	Anti-BCL3 Antibody See all BCL3 primary antibodies
Description:	Rabbit polyclonal antibody to BCL3
Specificity:	The antibody detects endogenous levels of total BCL3 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to residues near the N terminal of human B-cell CLL / lymphoma 3
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity).
Post-Translational Modification:	Polyubiquitinated. Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains. Deubiquitination by CYLD prevents nuclear accumulation (By similarity).
Cellular Location:	Nucleus. Cytoplasm. Cytoplasm > Perinuclear region. Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.
Database Links:	Entrez Gene: 602?Human Entrez Gene: 12051?Mouse Omim: 109560?Human SwissProt: P20749?Human SwissProt: Q9Z2F6?Mouse Unigene: 31210?Human
Synonyms:	B cell CLL/lymphoma 3 Antibody B cell leukemia/lymphoma 3 Antibody B cell lymphoma 3 encoded protein Antibody B-cell lymphoma 3 protein Antibody Bcl 3 Antibody BCL 4 Antibody BCL-3 Antibody Bcl3 Antibody BCL3_HUMAN Antibody BCL4 Antibody Chronic lymphatic leukemia protein Antibody D19S37 Antibody Protein Bcl 3 Antibody Proto-oncogene BCL3 Antibody
Information:	Target information shown above is from the UniProt Consortium.