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Anti-BAIAP2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-BAIAP2 Antibody

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Overview

Name:	Anti-BAIAP2 Antibody See all BAIAP2 primary antibodies
Description:	Rabbit polyclonal antibody to BAIAP2
Specificity:	The antibody detects endogenous level of total BAIAP2 protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human BAIAP2.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were purified by affinity purification using immunogen.
Concentration:	1.0mg / ml
Formulation:	Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
Tissue Specificity:	Isoform 1 and isoform 4 are expressed almost exclusively in brain. Isoform 4 is barely detectable in placenta, prostate and testis. A short isoform is ubiquitous, with the highest expression in liver, prostate, testis and placenta.
Post-Translational Modification:	Phosphorylated on tyrosine residues by INSR in response to insulin treatment.
Cellular Location:	Cytoplasm. Membrane. Cell projection > Filopodium. Cell projection > Ruffle. Cytoplasm > Cytoskeleton. Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles. Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.
Database Links:	Entrez Gene: 10458?Human Entrez Gene: 108100?Mouse Entrez Gene: 117542?Rat GenBank: NP_006331.1?Human Omim: 605475?Human SwissProt: Q9UQB8?Human SwissProt: Q8BKX1?Mouse SwissProt: Q6GMN2?Rat Unigene: 128316?Human Unigene: 197534?Mouse Unigene: 95155?Rat
Synonyms:	BAI-associated protein 2 Antibody BAI1 associated protein 2 Antibody BAI1-associated protein 2 Antibody BAIAP 2 Antibody BAIAP2 Antibody BAIP2_HUMAN Antibody BAP2 Antibody Brain-specific angiogenesis inhibitor 1-associated protein 2 Antibody Fas ligand-associated factor 3 Antibody FLAF3 Antibody Insulin receptor substrate p53 Antibody Insulin receptor substrate p53/p58 Antibody Insulin receptor substrate protein of 53 kDa Antibody IRS-58 Antibody IRSp53 Antibody IRSp53/58 Antibody Protein BAP2 Antibody
Information:	Target information shown above is from the UniProt Consortium.