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Anti-BAI2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-BAI2 Antibody

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Name:	Anti-BAI2 Antibody See all BAI2 primary antibodies
Description:	Rabbit polyclonal antibody to BAI2
Specificity:	The antibody detects endogenous levels of total BAI2 protein.
Applications:	IHC
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to residues near the C terminal of human brain-specific angiogenesis inhibitor 2
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.9mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Orphan receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT signaling pathway probably via a G-protein dependent pathway (PubMed:20367554). Might be involved in angiogenesis inhibition (By similarity).
Tissue Specificity:	Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
Sequence Similarities:	Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Post-Translational Modification:	Proteolytically cleaved at 2 conserved sites: one in the GPS domain (S1 site) and the other in the middle of the extracellular domain (S2 site). The proteolytic cleavage at S1 site generates an extracellular subunit and a seven-transmembrane subunit. Furin is involved in the cleavage of the S2 site generating a soluble fragment.
Cellular Location:	Cell membrane.
Database Links:	Entrez Gene: 576?Human Entrez Gene: 230775?Mouse Omim: 602683?Human SwissProt: O60241?Human SwissProt: Q8CGM1?Mouse Unigene: 200586?Human Unigene: 262241?Mouse
Synonyms:	BAI2 Antibody Brain Specific Angiogenesis Inhibitor 2 Antibody
Information:	Target information shown above is from the UniProt Consortium.