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Anti-BAI-1 (Q732) Antibody

品牌：Antibodies

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规格：50µl

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Anti-BAI-1 (Q732) Antibody

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Name:	Anti-BAI-1 (Q732) Antibody See all BAI1 primary antibodies
Description:	Rabbit polyclonal antibody to BAI-1 (Q732)
Specificity:	BAI-1 (Q732) pAb detects endogenous levels of BAI-1 protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 711-760 of Human BAI-1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 174 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain.
Tissue Specificity:	Specifically expressed in brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues. No expression in astrocytes.
Sequence Similarities:	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Post-Translational Modification:	The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
Cellular Location:	Cell membrane. Likely to be concentrated at cell-cell adhesion sites.
Database Links:	Entrez Gene: 575?Human Entrez Gene: 107831?Mouse Entrez Gene: 362931?Rat Omim: 602682?Human SwissProt: O14514?Human SwissProt: Q3UHD1?Mouse Unigene: 194654?Human Unigene: 43133?Mouse
Synonyms:	B830018M07Rik Antibody BAI 1 Antibody BAI1 Antibody BAI1_HUMAN Antibody Brain specific angiogenesis inhibitor 1 Antibody Brain-specific angiogenesis inhibitor 1 Antibody GDAIF Antibody KIAA4089 Antibody mKIAA4089 Antibody R75078 Antibody
Information:	Target information shown above is from the UniProt Consortium.