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Anti-BACE2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-BACE2 Antibody

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Overview

Name:	Anti-BACE2 Antibody See all BACE2 primary antibodies
Description:	Rabbit polyclonal antibody to BACE2
Applications:	E, WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Raised against a synthetic peptide corresponding to amino acids 44 to 59 of human BACE2.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target

Function:	Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672 (By similarity).
Sequence Similarities:	Belongs to the peptidase A1 family.
Post-Translational Modification:	Undergoes autoproteolytic cleavage.
Cellular Location:	Membrane. Golgi apparatus. Endoplasmic reticulum. Endosome. Cell surface.
Database Links:	Entrez Gene: 25825?Human Entrez Gene: 56175?Mouse Entrez Gene: 288227?Rat Omim: 605668?Human SwissProt: Q9Y5Z0?Human SwissProt: Q9JL18?Mouse SwissProt: Q6IE75?Rat Unigene: 529408?Human Unigene: 97885?Mouse Unigene: 38581?Rat
Synonyms:	ALP 56 Antibody ALP56 Antibody Asp 1 Antibody ASP1 Antibody ASP21 Antibody Aspartic Like Protease 56kDa Antibody Aspartic-like protease 56 kDa Antibody Aspartyl protease 1 Antibody BACE 2 Antibody BACE2 Antibody BACE2_HUMAN Antibody Beta Secretase 2 Antibody Beta Site Amyloid Beta A4 Precursor Protein Cleaving Enzyme 2 Antibody Beta-secretase 2 Antibody Beta-site amyloid precursor protein cleaving enzyme 2 Antibody Beta-site APP cleaving enzyme 2 Antibody Down region aspartic protease Antibody Downs Syndrome Region Aspartic Protease Antibody DRAP Antibody Memapsin 1 Antibody Memapsin-1 Antibody Membrane associated aspartic protease 1 Antibody Membrane-associated aspartic protease 1 Antibody Theta-secretase Antibody
Information:	Target information shown above is from the UniProt Consortium.