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Anti-ATXN7L3 Antibody

品牌：Antibodies

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规格：100µl

货期：

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Anti-ATXN7L3 Antibody

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Name:	Anti-ATXN7L3 Antibody See all ATXN7L3 primary antibodies
Description:	Rabbit polyclonal antibody to ATXN7L3
Specificity:	The antibody detects endogenous levels of total ATXN7L3 protein.
Applications:	IHC
Dilutions:	Immunohistochemistry: 1:100-1:200
Reactivity:	Human
Immunogen:	Fusion protein of human ATXN7L3
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2mg / ml
Formulation:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage:	Store at -20?C

Function:	Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Sequence Similarities:	Belongs to the SGF11 family.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 56970?Human SwissProt: Q14CW9?Human Unigene: 512651?Human
Synonyms:	AT7L3_HUMAN Antibody Ataxin 7 like 3 Antibody Ataxin 7 like protein 3 Antibody Ataxin-7-like protein 3 Antibody ATXN7L3 Antibody SAGA associated factor 11 homolog Antibody SAGA-associated factor 11 homolog Antibody
Information:	Target information shown above is from the UniProt Consortium.