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Anti-SLP-76 Antibody

品牌：Antibodies

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规格：50µl

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Anti-SLP-76 Antibody

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Name:	Anti-SLP-76 Antibody See all SLP-76 primary antibodies
Description:	Rabbit polyclonal antibody to SLP-76
Specificity:	SLP-76 pAb detects endogenous levels of SLP-76 protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant full length Human SLP-76.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 75 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.

Function:	Involved in T-cell antigen receptor mediated signaling.
Tissue Specificity:	Highly expressed in spleen, thymus and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines. Not detected in fibroblast or neuroblastoma cell lines.
Post-Translational Modification:	Phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2. SYK-dependent phosphorylation is required for recruitment of PI3K signaling components.
Cellular Location:	Cytoplasm.
Database Links:	Entrez Gene: 3937?Human Entrez Gene: 16822?Mouse Entrez Gene: 155918?Rat Omim: 601603?Human SwissProt: Q13094?Human SwissProt: Q60787?Mouse Unigene: 304475?Human Unigene: 265350?Mouse Unigene: 1057?Rat
Synonyms:	76 kDa tyrosine phosphoprotein Antibody CG8697 Antibody LCP 2 Antibody LCP2 Antibody LCP2_HUMAN Antibody Lymphocyte cytosolic protein 2 Antibody SH2 domain containing leukocyte protein 76 KD Antibody SH2 domain containing leukocyte protein of 76kD Antibody SH2 domain containing leukocyte protein of 76kDa Antibody SH2 domain-containing leukocyte protein of 76 kDa Antibody SLP 76 Antibody SLP 76 tyrosine phosphoprotein Antibody SLP-76 Antibody SLP-76 tyrosine phosphoprotein Antibody SLP76 Antibody SLP76 tyrosine phosphoprotein Antibody
Information:	Target information shown above is from the UniProt Consortium.