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Anti-SGCE Antibody

品牌：Antibodies

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规格：50µl

货期：

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Anti-SGCE Antibody

商品详情参考文献相关资料

Name:	Anti-SGCE Antibody See all SGCE primary antibodies
Description:	Rabbit polyclonal antibody to SGCE.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human SGCE.
Protein Length:	437
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Tissue Specificity:	Ubiquitous.
Involvement in Disease:	Dystonia 11, myoclonic: A myoclonic dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. DYT11 is characterized by involuntary lightning jerks and dystonic movements and postures alleviated by alcohol. Inheritance is autosomal dominant. The age of onset, pattern of body involvement, presence of myoclonus and response to alcohol are all variable.
Sequence Similarities:	Belongs to the sarcoglycan alpha/epsilon family.
Post-Translational Modification:	N-glycosylated.
Cellular Location:	Cell membrane > Sarcolemma. Cytoplasm > Cytoskeleton. Cell projection > Dendrite. Golgi apparatus.
Database Links:	Entrez Gene: 8910?Human Entrez Gene: 20392?Mouse Entrez Gene: 432360?Rat Omim: 604149?Human SwissProt: O43556?Human SwissProt: O70258?Mouse SwissProt: Q6YAT4?Rat Unigene: 371199?Human Unigene: 8739?Mouse Unigene: 185815?Rat
Synonyms:	dystonia 11, myoclonic Antibody DYT11 Antibody Epsilon sarcoglycan Antibody Epsilon SG Antibody Epsilon-sarcoglycan Antibody Epsilon-SG Antibody ESG Antibody sarcoglycan, epsilon Antibody SGCE Antibody SGCE_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.