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Anti-SF1 (Ab-82) Antibody

品牌：Antibodies

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规格：50µl

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Anti-SF1 (Ab-82) Antibody

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Name:	Anti-SF1 (Ab-82) Antibody See all SF1 primary antibodies
Description:	Rabbit polyclonal antibody to SF1 (Ab-82)
Specificity:	The antibody detects endogenous levels of total SF1 protein.
Applications:	WB, IHC, IF
Reactivity:	Human
Immunogen:	Synthesized non-phosphopeptide derived from human SF1 around the phosphorylation site of serine 82 (S-P-S(p)-P-E).
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Function:	Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.
Tissue Specificity:	Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart.
Sequence Similarities:	Belongs to the BBP/SF1 family.
Post-Translational Modification:	Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 2516?Human Omim: 184757?Human SwissProt: Q13285?Human Unigene: 495108?Human
Synonyms:	AD4BP Antibody Adrenal 4 binding protein Antibody Adrenal 4-binding protein Antibody ELP Antibody FTZ 1 Antibody FTZ1 Antibody FTZF 1 Antibody FTZF1 Antibody Fushi tarazu factor (Drosophila) homolog 1 Antibody Fushi tarazu factor homolog 1 Antibody hSF 1 Antibody NR5A1 Antibody Nuclear receptor AdBP4 Antibody Nuclear receptor subfamily 5 group A member 1 Antibody POF7 Antibody SF 1 Antibody SF-1 Antibody SF1 Antibody SPGF8 Antibody SRXY3 Antibody Steroid hormone receptor Ad4BP Antibody Steroidogenic Factor 1 Antibody Steroidogenic factor 1 nuclear receptor Antibody STF 1 Antibody STF-1 Antibody STF1 Antibody STF1_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.