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Anti-SEC61A1 Antibody

品牌：Antibodies

货号：

规格：100µg

货期：

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Anti-SEC61A1 Antibody

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Name:	Anti-SEC61A1 Antibody See all SEC61A1 primary antibodies
Description:	Goat polyclonal antibody to SEC61A1.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human SEC61A1 (C terminal).
Sequence:	C-KEQSEVGSMGALLF
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins. Plays a role in pronephric kidney tubule development (By similarity).
Involvement in Disease:	Familial juvenile hyperuricemic nephropathy 4: An autosomal dominant renal disorder characterized by progressive chronic kidney disease, anemia, elevated serum creatinine levels, and hyperuricemia.
Sequence Similarities:	Belongs to the SecY/SEC61-alpha family.
Cellular Location:	Endoplasmic reticulum membrane. Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Database Links:	Entrez Gene: 29927 Human Omim: 609213 Human SwissProt: P61619 Human Unigene: 518236 Human
Synonyms:	chunp6898 Antibody fb62c11 Antibody HSEC61 Antibody protein transport protein SEC61 alpha subunit Antibody protein transport protein Sec61 subunit alpha Antibody Protein transport protein Sec61 subunit alpha isoform 1 Antibody S61A1_HUMAN Antibody SEC 61 Antibody SEC 61A Antibody SEC61 Antibody Sec61 alpha 1 Antibody Sec61 alpha 1 subunit Antibody Sec61 alpha 1 subunit (S. cerevisiae) Antibody Sec61 alpha-1 Antibody Sec61 homolog Antibody SEC61A Antibody SEC61A1 Antibody sec61aa Antibody
Information:	Target information shown above is from the UniProt Consortium.