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Anti-Sec61 alpha-1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-Sec61 alpha-1 Antibody

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Name:	Anti-Sec61 alpha-1 Antibody See all Sec61 alpha-1 primary antibodies
Description:	Rabbit polyclonal antibody to Sec61 alpha-1
Applications:	WB, IHC, IF
Reactivity:	Human
Immunogen:	Synthetic peptide contain a sequence corresponding to a region within amino acids 413 and 476 of Sec61 alpha-1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 1XPBS, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.

Function:	Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins. Plays a role in pronephric kidney tubule development (By similarity).
Involvement in Disease:	Familial juvenile hyperuricemic nephropathy 4: An autosomal dominant renal disorder characterized by progressive chronic kidney disease, anemia, elevated serum creatinine levels, and hyperuricemia.
Sequence Similarities:	Belongs to the SecY/SEC61-alpha family.
Cellular Location:	Endoplasmic reticulum membrane. Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Database Links:	Entrez Gene: 29927?Human Omim: 609213?Human SwissProt: P61619?Human Unigene: 518236?Human
Synonyms:	chunp6898 Antibody fb62c11 Antibody HSEC61 Antibody protein transport protein SEC61 alpha subunit Antibody protein transport protein Sec61 subunit alpha Antibody Protein transport protein Sec61 subunit alpha isoform 1 Antibody S61A1_HUMAN Antibody SEC 61 Antibody SEC 61A Antibody SEC61 Antibody Sec61 alpha 1 Antibody Sec61 alpha 1 subunit Antibody Sec61 alpha 1 subunit (S. cerevisiae) Antibody Sec61 alpha-1 Antibody Sec61 homolog Antibody SEC61A Antibody SEC61A1 Antibody sec61aa Antibody
Information:	Target information shown above is from the UniProt Consortium.