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Anti-SDCBP2 Antibody

品牌：Antibodies

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规格：100µg

货期：

应用：

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Anti-SDCBP2 Antibody

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Overview

Name:	Anti-SDCBP2 Antibody See all SDCBP2 primary antibodies
Description:	Goat polyclonal antibody to SDCBP2.
Applications:	ELISA, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human SDCBP2 (C terminal).
Sequence:	C-LLHHTMDHSIPDA
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival (PubMed:15961997).
Tissue Specificity:	Preferentially expressed in cells of the digestive tract (PubMed:11102519). Low expression in skeletal muscle and kidney (PubMed:11102519). Detected in differentiated keratinocytes of normal and malignant epithelium (PubMed:22623796). In healthy skin, expression is localized in suprabasal epidermal layers (PubMed:22623796).
Cellular Location:	Cytoplasm. Nucleus > Nucleolus. Nucleus > Nucleoplasm. Cell membrane. Nucleus speckle. Associates with intracellular membranes and enriched in the apical region of the cell and in intracellular compartments (PubMed:11102519). Colocalizes with TM4SF1 in the apical region of the cell (PubMed:11102519). Predominantly targeted to nuclear PIP2 pools. Shuttles between several subcellular compartments (PubMed:15961997). PIP2 plays an important role in the distribution of SDCBP2 (PubMed:23300061).
Database Links:	Entrez Gene: 27111?Human GenBank: NP_056500?Human GenBank: NP_536737?Human Omim: 602217?Human SwissProt: Q9H190?Human Unigene: 657015?Human
Synonyms:	MDA9 Antibody Melanoma differentiation associated gene 9 Antibody Pro TGF alpha cytoplasmic domain interacting protein 18 Antibody SDCB2_HUMAN Antibody SDCBP2 Antibody SITAC Antibody SITAC18 Antibody ST 2 Antibody Syndecan binding protein (syntenin) 2 Antibody Syndecan binding protein 2 Antibody Syndecan-binding protein 2 Antibody Syntenin 2 Antibody Syntenin-2 Antibody
Information:	Target information shown above is from the UniProt Consortium.