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Anti-SAE1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-SAE1 Antibody

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Name:	Anti-SAE1 Antibody See all SAE1 primary antibodies
Description:	Rabbit polyclonal antibody to SAE1
Applications:	WB, IHC, IF
Reactivity:	Human
Immunogen:	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 3 and 217 of SAE1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 0.1M Tris-buffered saline with 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.

Function:	The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Tissue Specificity:	Expression level increases during S phase and drops in G2 phase (at protein level).
Sequence Similarities:	Belongs to the ubiquitin-activating E1 family.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 10055?Human Omim: 613294?Human SwissProt: Q9UBE0?Human Unigene: 515500?Human
Synonyms:	Activator of SUMO1 Antibody AOS1 Antibody HSPC140 Antibody SAE1 Antibody SAE1_HUMAN Antibody Sentrin/SUMO activating protein AOS1 Antibody SUA1 Antibody SUMO 1 activating enzyme E1 N subunit Antibody SUMO 1 activating enzyme subunit 1 Antibody SUMO-activating enzyme subunit 1 Antibody Ubiquitin like protein SUMO1 activating enzyme Antibody Ubiquitin-like 1-activating enzyme E1A Antibody UBL E1A Antibody UBLE1A Antibody
Information:	Target information shown above is from the UniProt Consortium.