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Anti-RPS10 Antibody

品牌：Antibodies

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规格：50µl

货期：

应用：

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Anti-RPS10 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-RPS10 Antibody See all RPS10 primary antibodies
Description:	Rabbit polyclonal antibody to RPS10.
Applications:	WB, IHC, IF, IP
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:20 - 1:50, IP: 1:20 - 1:50.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human RPS10.
Protein Length:	165
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Component of the 40S ribosomal subunit.
Involvement in Disease:	Diamond-Blackfan anemia 9: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
Sequence Similarities:	Belongs to the ribosomal protein S10e family.
Post-Translational Modification:	Methylated by PRMT5. Methylation is necessary for its interaction with NPS1, its localization in the granular component (GC) region of the nucleolus, for the proper assembly of ribosomes, protein synthesis and optimal cell proliferation.
Cellular Location:	Cytoplasm. Nucleus > Nucleolus. Localized in the granular component (GC) region of the nucleolus. Methylation is required for its localization in the GC region. Colocalizes with NPS1 in the GC region of the nucleolus.
Database Links:	Entrez Gene: 6204?Human Entrez Gene: 67097?Mouse Entrez Gene: 100363439?Rat Entrez Gene: 100364787?Rat Entrez Gene: 81773?Rat Omim: 603632?Human SwissProt: P46783?Human SwissProt: P63325?Mouse SwissProt: P63326?Rat Unigene: 406620?Human Unigene: 645317?Human Unigene: 275810?Mouse Unigene: 383217?Mouse Unigene: 3359?Rat
Synonyms:	40S ribosomal protein S10 Antibody DBA9 Antibody MGC88819 Antibody OTTHUMP00000016229 Antibody OTTHUMP00000016230 Antibody Ribosomal protein S10 Antibody RPS10 Antibody RS10_HUMAN Antibody S10 Antibody
Information:	Target information shown above is from the UniProt Consortium.