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Anti-WIPI2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-WIPI2 Antibody

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Name:	Anti-WIPI2 Antibody See all WIPI2 primary antibodies
Description:	Rabbit polyclonal antibody to WIPI2.
Applications:	WB, IHC
Dilutions:	WB: 1:200 - 1:2000, IHC: 1:50 - 1:200.
Reactivity:	Human
Immunogen:	A synthetic peptide of human WIPI2.
Protein Length:	454
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to phosphatidylinositol 3-phosphate (PtdIns3P). May bind PtdIns3P.
Tissue Specificity:	Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors.
Sequence Similarities:	Belongs to the WD repeat SVP1 family.
Cellular Location:	Preautophagosomal structure membrane. Localizes to omegasomes membranes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P.
Database Links:	Entrez Gene: 26100?Human Omim: 609225?Human SwissProt: Q9Y4P8?Human Unigene: 122363?Human
Synonyms:	ATG18B Antibody Atg21 Antibody CGI 50 Antibody DKFZp434J154 Antibody DKFZp686P02188 Antibody FLJ12979 Antibody FLJ14217 Antibody FLJ42984 Antibody WD repeat domain phosphoinositide-interacting protein 2 Antibody WD repeat domain, phosphoinositide interacting 2 Antibody WD40 repeat protein interacting with phosphoinositides 2 Antibody WIPI 2 Antibody WIPI-2 Antibody WIPI2 Antibody WIPI2_HUMAN Antibody WIPI49 like protein 2 Antibody WIPI49-like protein 2 Antibody
Information:	Target information shown above is from the UniProt Consortium.