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Anti-WDR5 Antibody

品牌：Antibodies

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规格：100µl

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Anti-WDR5 Antibody

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Name:	Anti-WDR5 Antibody See all WDR5 primary antibodies
Description:	Mouse monoclonal antibody to WDR5.
Applications:	WB, IF, IP
Dilutions:	WB: 1:500 - 1:2000, IF: 1:50 - 1:100, IP: 1:20 - 1:50.
Reactivity:	Human, Mouse, Rat
Immunogen:	A synthetic peptide of human WDR5.
Host:	Mouse
Clonality:	Monoclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Sequence Similarities:	Belongs to the WD repeat WDR5/wds family.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 11091 Human Entrez Gene: 140858 Mouse Entrez Gene: 362093 Rat Omim: 609012 Human SwissProt: P61964 Human SwissProt: P61965 Mouse SwissProt: Q498M4 Rat Unigene: 397638 Human Unigene: 28265 Mouse Unigene: 106818 Rat
Synonyms:	2410008O07Rik Antibody AA408785 Antibody AA960360 Antibody Big Antibody BIG 3 Antibody BIG3 Antibody BMP2 induced 3 kb gene protein Antibody BMP2 induced gene, 3-KB Antibody BMP2-induced 3-kb gene protein Antibody MGC114572 Antibody OTTHUMP00000162494 Antibody SWD 3 Antibody SWD3 Antibody SWD3 Set1c WD40 repeat protein homolog Antibody WD repeat containing protein 5 Antibody WD repeat domain 5 Antibody WD repeat protein 5 Antibody WD repeat-containing protein 5 Antibody WD repeat-containing protein BIG-3 Antibody WDR 5 Antibody WDR5 Antibody WDR5_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.