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Anti-WDR18 Antibody

品牌：Antibodies

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规格：100µl

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Anti-WDR18 Antibody

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Name:	Anti-WDR18 Antibody See all WDR18 primary antibodies
Description:	Rabbit polyclonal antibody to WDR18
Specificity:	WDR18 antibody is predicted to not cross-react with other WDR family members.
Applications:	E, WB
Reactivity:	Human, Mouse, Rat
Immunogen:	17 amino acid peptide near the carboxy terminus of human WDR18.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	PBS containing 0.02% sodium azide.
Storage:	Store at 4˚C for three months and -20˚C, stable for up to one year.

Function:	Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity).
Sequence Similarities:	Belongs to the WD repeat IPI3/WDR18 family.
Cellular Location:	Nucleus > Nucleolus. Nucleus > Nucleoplasm. Cytoplasm. Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions.
Database Links:	Entrez Gene: 57418 Human Entrez Gene: 216156 Mouse Entrez Gene: 314617 Rat SwissProt: Q9BV38 Human SwissProt: Q4VBE8 Mouse SwissProt: Q499N3 Rat Unigene: 325321 Human Unigene: 35828 Mouse Unigene: 229161 Rat Unigene: 23448 Rat
Synonyms:	Involved in Processing ITS2 3 homolog Antibody Ipi3 Antibody MGC2436 Antibody R32184_1 Antibody WD repeat domain 18 Antibody WD repeat-containing protein 18 Antibody WDR18 Antibody WDR18_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.