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Anti-HERPUD1 Antibody

品牌：Antibodies

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规格：50µl

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Anti-HERPUD1 Antibody

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Overview

Name:	Anti-HERPUD1 Antibody See all HERPUD1 primary antibodies
Description:	Rabbit polyclonal antibody to HERPUD1.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity:	Human
Immunogen:	Recombinant protein of human HERPUD1.
Protein Length:	391
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway (PubMed:18307982).
Tissue Specificity:	Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease.
Cellular Location:	Endoplasmic reticulum membrane.
Database Links:	Entrez Gene: 9709?Human Omim: 608070?Human SwissProt: Q15011?Human Unigene: 146393?Human
Synonyms:	HERP Antibody HERP1_HUMAN Antibody HERPUD1 Antibody Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 1 Antibody Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 1 protein Antibody Homocysteine responsive endoplasmic reticulum resident ubiquitin like domain member 1 Antibody Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein Antibody KIAA0025 Antibody Methyl methanesulfonate (MMF) inducible fragment protein 1 Antibody Methyl methanesulfonate (MMF)-inducible fragment protein 1 Antibody MIF1 Antibody MMS inducible Antibody SUP Antibody
Information:	Target information shown above is from the UniProt Consortium.