Anti-SERPINE1 Antibody |产品详情|进口试剂采购网

您好，欢迎来到拜力生物网站！请登录注册

我的订单 | 联系我们 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA试剂盒、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口试剂、Quidel代理、Swant代理、PBL Assay Science代理

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-SERPINE1 Antibody

品牌：Antibodies

货号：

规格：100µl

货期：

立即购买加入购物车

Anti-SERPINE1 Antibody

商品详情参考文献相关资料

Name:	Anti-SERPINE1 Antibody See all SERPINE1 primary antibodies
Description:	Rabbit polyclonal antibody to SERPINE1
Specificity:	The antibody detects endogenous levels of total SERPINE1 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	0.6mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
Tissue Specificity:	Found in plasma and platelets and in endothelial, hepatoma and fibrosarcoma cells.
Involvement in Disease:	Plasminogen activator inhibitor-1 deficiency: A hematologic disorder characterized by increased bleeding after trauma, injury, or surgery. Affected females have menorrhagia. The bleeding defect is due to increased fibrinolysis of fibrin blood clots due to deficiency of plasminogen activator inhibitor-1, which inhibits tissue and urinary activators of plasminogen.
Sequence Similarities:	Belongs to the serpin family.
Post-Translational Modification:	Inactivated by proteolytic attack of the urokinase-type (u-PA) and the tissue-type (TPA), cleaving the 369-Arg-\|-Met-370 bond.
Cellular Location:	Secreted.