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Anti-SEPT4 Antibody

品牌：Antibodies

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规格：100µg

货期：

应用：

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Anti-SEPT4 Antibody

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Overview

Name:	Anti-SEPT4 Antibody See all SEPT4 primary antibodies
Description:	Goat polyclonal antibody to SEPT4.
Applications:	ELISA, WB
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to Human SEPT4 (internal region).
Sequence:	C-RNKLTRESGTD
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 µg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity).
Tissue Specificity:	Expressed in the brain. Abundant in areas of high cell density, particularly in the stria terminalis. Isoform 4 is predominantly expressed in embryonic mouse brain and dorsal root ganglion neurons.
Sequence Similarities:	Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Cellular Location:	Cytoplasm. Cytoplasm > Cytoskeleton. Cell projection > Cilium > Flagellum. Found in the sperm annulus.
Database Links:	Entrez Gene: 5414 Human Entrez Gene: 18952 Mouse Omim: 603696 Human SwissProt: O43236 Human SwissProt: P28661 Mouse Unigene: 287518 Human Unigene: 2214 Mouse
Synonyms:	Apoptosis-related protein in the TGF-beta signaling pathway Antibody ARTS Antibody Bradeion Antibody Bradeion beta Antibody Brain protein H5 Antibody CE5B3 Antibody CE5B3 beta Antibody Cell division control-related protein 2 Antibody Cerebral protein 7 Antibody H5 Antibody hCDCREL-2 Antibody hucep-7 Antibody MART Antibody Peanut-like protein 2 Antibody PNUTL2 Antibody SEP 4 Antibody SEP4 Antibody SEPT4 Antibody SEPT4_HUMAN Antibody Septin M Antibody Septin-4 Antibody
Information:	Target information shown above is from the UniProt Consortium.