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Anti-Separase (A795) Antibody

品牌：Antibodies

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规格：50µl

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Anti-Separase (A795) Antibody

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Name:	Anti-Separase (A795) Antibody See all Separase primary antibodies
Description:	Rabbit polyclonal antibody to Separase (A795)
Specificity:	Separase (A795) pAb detects endogenous levels of Separase protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 763-824 of Human Separase.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 230 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
Post-Translational Modification:	Autocleaves. This function, which is not essential for its protease activity, is unknown.
Cellular Location:	Cytoplasm. Nucleus.
Database Links:	Entrez Gene: 9700?Human Entrez Gene: 105988?Mouse Omim: 604143?Human SwissProt: Q14674?Human SwissProt: P60330?Mouse Unigene: 153479?Human Unigene: 288324?Mouse
Synonyms:	Caspase like protein ESPL1 Antibody Caspase-like protein ESPL1 Antibody ESP 1 Antibody ESP1 Antibody ESPL 1 Antibody Espl1 Antibody ESPL1_HUMAN Antibody Extra spindle poles like 1 Antibody Extra spindle poles like 1 protein Antibody Extra spindle poles-like 1 protein Antibody FLJ46492 Antibody KIAA0165 Antibody Separase Antibody Separin Antibody Similar to fission yeast cut1and gene Antibody SSE Antibody
Information:	Target information shown above is from the UniProt Consortium.