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Anti-SENP2 (L512) Antibody

品牌：Antibodies

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规格：50µl

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Anti-SENP2 (L512) Antibody

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Name:	Anti-SENP2 (L512) Antibody See all SENP2 primary antibodies
Description:	Rabbit polyclonal antibody to SENP2 (L512)
Specificity:	SENP2 (L512) pAb detects endogenous levels of SENP2 protein.
Applications:	WB, IHC
Reactivity:	Human, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 482-530 of Human SENP2.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 68 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).
Sequence Similarities:	Belongs to the peptidase C48 family.
Post-Translational Modification:	Polyubiquitinated; which leads to proteasomal degradation.
Cellular Location:	Nucleus > Nuclear pore complex. Nucleus membrane. Cytoplasm. Shuttles between cytoplasm and nucleus.
Database Links:	Entrez Gene: 59343?Human Entrez Gene: 78973?Rat Omim: 608261?Human SwissProt: Q9HC62?Human SwissProt: Q9EQE1?Rat Unigene: 401388?Human Unigene: 9367?Rat
Synonyms:	Axam2 Antibody DKFZp762A2316 Antibody KIAA1331 Antibody SENP2 Antibody SENP2_HUMAN Antibody Sentrin specific protease 2 Antibody Sentrin-specific protease 2 Antibody Sentrin/SUMO specific protease SENP2 Antibody Sentrin/SUMO-specific protease SENP2 Antibody SMT3 specific isopeptidase 2 Antibody SMT3-specific isopeptidase 2 Antibody Smt3ip2 Antibody SUMO1/sentrin/SMT3 specific peptidase 2 Antibody
Information:	Target information shown above is from the UniProt Consortium.