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Anti-RHOT1 Antibody

品牌：Antibodies

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规格：50µl

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Anti-RHOT1 Antibody

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Name:	Anti-RHOT1 Antibody See all RHOT1 primary antibodies
Description:	Rabbit polyclonal antibody to RHOT1.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:100.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human RHOT1.
Protein Length:	618
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
Tissue Specificity:	Ubiquitously expressed. Expressed at high level in heart and skeletal muscle.
Sequence Similarities:	Belongs to the mitochondrial Rho GTPase family.
Post-Translational Modification:	Ubiquitinated by PARK2 during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
Cellular Location:	Mitochondrion outer membrane. Colocalizes with MGARP and RHOT2 at the mitochondria.
Database Links:	Entrez Gene: 55288?Human Entrez Gene: 59040?Mouse Entrez Gene: 303351?Rat Omim: 613888?Human SwissProt: Q8IXI2?Human SwissProt: Q8BG51?Mouse Unigene: 655325?Human Unigene: 489674?Mouse Unigene: 7462?Rat
Synonyms:	ARHT 1 Antibody ARHT1 Antibody FLJ11040 Antibody FLJ12633 Antibody hMiro 1 Antibody hMiro-1 Antibody hMiro1 Antibody MIRO 1 Antibody MIRO-1 Antibody MIRO1 Antibody MIRO1_HUMAN Antibody mitochondrial Rho (MIRO) GTPase 1 Antibody Mitochondrial Rho 1 Antibody Mitochondrial Rho GTPase 1 Antibody Mitochondrial Rho1 Antibody Rac GTP binding protein like protein Antibody Rac-GTP-binding protein-like protein Antibody Ras homolog family member T1 Antibody Ras homolog gene family member T1 Antibody Rhot 1 Antibody RHOT1 Antibody
Information:	Target information shown above is from the UniProt Consortium.