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Anti-RGS10 Antibody

品牌：Antibodies

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规格：50µl

货期：

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Anti-RGS10 Antibody

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Name:	Anti-RGS10 Antibody See all RGS10 primary antibodies
Description:	Rabbit polyclonal antibody to RGS10
Specificity:	RGS10 pAb detects endogenous levels of RGS10 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 357-402 of Human RGS10.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 20 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling (PubMed:11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein (PubMed:9353196).
Post-Translational Modification:	Isoform 3 is phosphorylated on Ser-16.
Cellular Location:	Cytoplasm > Cytosol. Nucleus. Forskolin treatment promotes phosphorylation and translocation to the nucleus.
Database Links:	Entrez Gene: 6001?Human Entrez Gene: 67865?Mouse Entrez Gene: 54290?Rat Omim: 602856?Human SwissProt: O43665?Human SwissProt: Q9CQE5?Mouse SwissProt: P49806?Rat Unigene: 501200?Human Unigene: 18635?Mouse Unigene: 23957?Rat
Synonyms:	Regulator of G protein signaling 10 Antibody Regulator of G-protein signaling 10 Antibody RGS10 Antibody RGS10_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.