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Anti-RanBP9 Antibody

品牌：Antibodies

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规格：50µl

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Anti-RanBP9 Antibody

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Overview

Name:	Anti-RanBP9 Antibody See all RanBP9 primary antibodies
Description:	Mouse IgG1 monoclonal antibody to RanBP9
Specificity:	This antibody detects endogenous levels of RanBP9 and does not cross-react with related proteins
Applications:	WB, IP, ICC
Reactivity:	Human
Immunogen:	Recombinant full length Human RanBP9.
Host:	Mouse IgG1
Clonality:	Monoclonal
Conjugate:	Unconjugated
Molecular Weight:	Predicted band size:78KDa Observed band size:95KDa
Purity:	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Target

Function:	May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA (By similarity).
Tissue Specificity:	Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.
Sequence Similarities:	Belongs to the RANBP9/10 family.
Post-Translational Modification:	Phosphorylated in response to stress. Can be phosphorylated by the cleaved p110 form of CDC2L1 (p110C).
Cellular Location:	Cytoplasm. Nucleus. Cell membrane. The unphosphorylated form is predominantly cytoplasmic. A phosphorylated form is associated with the plasma membrane.
Database Links:	Entrez Gene: 10048 Human Omim: 603854 Human SwissProt: Q96S59 Human Unigene: 708182 Human
Synonyms:	B cell antigen receptor Ig beta associated protein 1 Antibody BPM 90 Antibody BPM L Antibody BPM-L Antibody BPM90 Antibody BPML Antibody IBAP 1 Antibody Imp 9 Antibody Importin 9 Antibody Novel centrosomal protein RanBPM Antibody RAN binding protein 9 Antibody Ran binding protein centrosomal Antibody Ran Binding Protein in the Microtubule organizing center Antibody Ran binding protein M Antibody Ran BP9 Antibody Ran-binding protein 9 Antibody Ran-binding protein M Antibody RANB9_HUMAN Antibody RanBP 7 Antibody RANBP 9 Antibody RanBP7 Antibody RanBP9 Antibody RanBPM Antibody
Information:	Target information shown above is from the UniProt Consortium.