Anti-Rab5 Antibody |产品详情|进口试剂采购网

您好，欢迎来到拜力生物网站！请登录注册

我的订单 | 联系我们 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA试剂盒、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口试剂、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于我们

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-Rab5 Antibody

品牌：Antibodies

货号：

规格：100µl

货期：

应用：

咨询客服

立即购买加入购物车

Anti-Rab5 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-Rab5 Antibody See all Rab5 primary antibodies
Description:	Rabbit monoclonal antibody to Rab5.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:1000, IHC: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human RAB5A.
Host:	Rabbit
Clonality:	Monoclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity).
Sequence Similarities:	Belongs to the small GTPase superfamily. Rab family.
Cellular Location:	Cell membrane. Early endosome membrane. Melanosome. Cytoplasmic vesicle. Cell projection > Ruffle. Membrane. Cytoplasm > Cytosol. Cytoplasmic vesicle > Phagosome membrane. Endosome membrane. Enriched in stage I melanosomes (PubMed:17081065). Alternates between membrane-bound and cytosolic forms (Probable).
Database Links:	Entrez Gene: 5868?Human Entrez Gene: 271457?Mouse Entrez Gene: 64633?Rat Omim: 179512?Human SwissProt: P20339?Human SwissProt: Q9CQD1?Mouse SwissProt: M0RC99?Rat Unigene: 475663?Human Unigene: 329123?Mouse Unigene: 44477?Rat
Synonyms:	RAB 5 Antibody RAB 5A Antibody Rab5 Antibody RAB5A Antibody RAB5A member RAS oncogene family Antibody RAB5A_HUMAN Antibody RAS associated protein RAB5A Antibody Ras related protein Rab 5A Antibody Ras-related protein Rab-5A Antibody
Information:	Target information shown above is from the UniProt Consortium.