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Anti-ATF3 (N159) Antibody

品牌：Antibodies

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规格：50µl

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Anti-ATF3 (N159) Antibody

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Name:	Anti-ATF3 (N159) Antibody See all ATF3 primary antibodies
Description:	Rabbit polyclonal antibody to ATF3 (N159)
Specificity:	ATF-3 (N159) pAb detects endogenous levels of ATF-3 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 120-170 of Human ATF3.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 21 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Sequence Similarities:	Belongs to the bZIP family. ATF subfamily.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 467?Human Entrez Gene: 11910?Mouse Entrez Gene: 25389?Rat Omim: 603148?Human SwissProt: P18847?Human SwissProt: Q60765?Mouse SwissProt: P29596?Rat Unigene: 460?Human Unigene: 2706?Mouse Unigene: 9664?Rat
Synonyms:	Activating transcription factor 3 Antibody ATF3 Antibody ATF3deltaZip2 Antibody ATF3deltaZip2c Antibody ATF3deltaZip3 Antibody ATF3_HUMAN Antibody cAMP dependent transcription factor ATF3 Antibody cAMP-dependent transcription factor ATF-3 Antibody Cyclic AMP dependent transcription factor ATF3 Antibody Cyclic AMP-dependent transcription factor ATF-3 Antibody
Information:	Target information shown above is from the UniProt Consortium.