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Anti-ASCL1 (E158) Antibody

品牌：Antibodies

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规格：50µl

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Anti-ASCL1 (E158) Antibody

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Overview

Name:	Anti-ASCL1 (E158) Antibody See all ASCL1 primary antibodies
Description:	Rabbit polyclonal antibody to ASCL1 (E158)
Specificity:	ASCL1 (E158) pAb detects endogenous levels of ASCL1 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 140-190 of Human ASCL1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 25 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Target

Function:	Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 429?Human Entrez Gene: 17172?Mouse Entrez Gene: 64186?Rat Omim: 100790?Human SwissProt: P50553?Human SwissProt: Q02067?Mouse SwissProt: P19359?Rat Unigene: 703025?Human Unigene: 136217?Mouse Unigene: 32936?Rat
Synonyms:	Achaete scute complex homolog 1 Antibody Achaete scute complex homolog like 1 Antibody Achaete scute complex homologue 1 Antibody Achaete scute complex homologue like 1 Antibody Achaete scute complex like 1 Antibody Achaete scute family bHLH transcription factor 1 Antibody Achaete scute protein Antibody Achaete-scute homolog 1 Antibody Ascl 1 Antibody ascl1 Antibody ASCL1_HUMAN Antibody Ash 1 Antibody ASH-1 Antibody Ash1 Antibody bHLHa46 Antibody Class A basic helix-loop-helix protein 46 Antibody Hash 1 Antibody HASH1 Antibody Mammalian achaete scute homolog 1 Antibody Mammalian achaete scute homologue 1 Antibody Mash 1 Antibody Mash1 Antibody MASH1/Achaete-scute homolog 1 Antibody
Information:	Target information shown above is from the UniProt Consortium.