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Anti-AQP4 (P253) Antibody

品牌：Antibodies

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规格：50µl

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Anti-AQP4 (P253) Antibody

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Name:	Anti-AQP4 (P253) Antibody See all AQP4 primary antibodies
Description:	Rabbit polyclonal antibody to AQP4 (P253)
Specificity:	AQP4 (P253) pAb detects endogenous levels of AQP4 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 220-270 of Human AQP4.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 35 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
Tissue Specificity:	Brain - muscle >> heart, kidney, lung, and trachea.
Sequence Similarities:	Belongs to the MIP/aquaporin (TC 1.A.8) family.
Post-Translational Modification:	Phosphorylation by PKC at Ser-180 reduces conductance by 50%. Phosphorylation by PKG at Ser-111 in response to glutamats increases conductance by 40% (By similarity).
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 361?Human Entrez Gene: 11829?Mouse Entrez Gene: 25293?Rat Omim: 600308?Human SwissProt: P55087?Human SwissProt: P55088?Mouse SwissProt: P47863?Rat Unigene: 315369?Human Unigene: 250786?Mouse Unigene: 90091?Rat
Synonyms:	AQP 4 Antibody AQP-4 Antibody AQP4 Antibody AQP4_HUMAN Antibody Aquaporin 4 Antibody Aquaporin type 4 Antibody Aquaporin-4 Antibody Aquaporin4 Antibody HMIWC 2 Antibody HMIWC2 Antibody Mercurial insensitive water channel Antibody Mercurial-insensitive water channel Antibody MGC22454 Antibody MIWC Antibody WCH 4 Antibody WCH4 Antibody
Information:	Target information shown above is from the UniProt Consortium.