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Anti-AKR1A1 Antibody

品牌：Antibodies

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规格：50µl

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Anti-AKR1A1 Antibody

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Overview

Name:	Anti-AKR1A1 Antibody See all AKR1A1 primary antibodies
Description:	Rabbit polyclonal antibody to AKR1A1.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human AKR1A1.
Protein Length:	325
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Tissue Specificity:	Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.
Sequence Similarities:	Belongs to the aldo/keto reductase family.
Database Links:	Entrez Gene: 10327?Human Entrez Gene: 58810?Mouse Entrez Gene: 78959?Rat Omim: 103830?Human SwissProt: P14550?Human SwissProt: Q9JII6?Mouse SwissProt: P51635?Rat Unigene: 474584?Human Unigene: 30085?Mouse Unigene: 835?Rat
Synonyms:	AK1A1_HUMAN Antibody AKR1A1 Antibody Alcohol dehydrogenase Antibody Alcohol dehydrogenase [NADP+] Antibody Aldehyde reductase Antibody Aldo keto reductase family 1 member A1 (aldehyde reductase) Antibody Aldo-keto reductase family 1 member A1 Antibody ALDR1 Antibody ALR Antibody ARM Antibody DD3 Antibody MGC12529 Antibody MGC1380 Antibody
Information:	Target information shown above is from the UniProt Consortium.