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Anti-PUMA Antibody

品牌：Antibodies

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规格：50µl

货期：

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Anti-PUMA Antibody

商品详情参考文献相关资料

Name:	Anti-PUMA Antibody See all PUMA primary antibodies
Description:	Rabbit monoclonal antibody to PUMA
Specificity:	This antibody detects endogenous levels of PUMA and does not cross-react with related proteins.
Applications:	WB, ICC/IF, IHC, FC
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant antibody.
Host:	Rabbit
Clonality:	Monoclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 20 kDa
Purity:	Protein A affinity purified
Product Form:	Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Function:	Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Tissue Specificity:	Ubiquitously expressed.
Sequence Similarities:	Belongs to the Bcl-2 family.
Cellular Location:	Mitochondrion. Localized to the mitochondria in order to induce cytochrome c release.
Database Links:	Entrez Gene: 27113?Human Entrez Gene: 170770?Mouse Entrez Gene: 317673?Rat Omim: 605854?Human SwissProt: Q9BXH1?Human SwissProt: Q99ML1?Mouse SwissProt: Q80ZG6?Rat Unigene: 467020?Human Unigene: 7660?Mouse Unigene: 25176?Rat
Synonyms:	BBC 3 Antibody Bbc3 Antibody BBC3_HUMAN Antibody BCL 2 binding component 3 Antibody Bcl-2-binding component 3 Antibody BCL2 binding component 3 Antibody JFY 1 Antibody JFY-1 Antibody JFY1 Antibody p53 up regulated modulator of apoptosis Antibody p53 up-regulated modulator of apoptosis Antibody p53 Upregulated Modulator of Apoptosis Antibody PUMA Antibody PUMA alpha Antibody PUMA/JFY1 Antibody
Information:	Target information shown above is from the UniProt Consortium.