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Anti-MBP Antibody

品牌：Antibodies

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规格：50µl

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Anti-MBP Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-MBP Antibody See all Myelin Basic Protein primary antibodies
Description:	Mouse monoclonal (7G7) antibody to MBP.
Applications:	WB, IF/ICC, IHC
Dilutions:	WB:1:5,000 -1:10,000. IF/ICC and IHC: 1:1,000.
Reactivity:	Human, Horse, Cow, Porcine, Chicken, Rat, Mouse
Immunogen:	Purified myelin basic protein isolated from cow nerve.
Host:	Mouse
Clonality:	Monoclonal
Clone:	7G7
Isotype:	IgG1
Conjugate:	Unconjugated
Purification:	Immunogen affinity purified.
Concentration:	1 mg/ml
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline with 50% Glycerol and 5mM Sodium Azide.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).
Tissue Specificity:	Found in both the central and the peripheral nervous system.
Sequence Similarities:	Belongs to the myelin basic protein family.
Post-Translational Modification:	As in other animals, several charge isomers may be produced as a result of optional post-translational modifications, such as phosphorylation of serine or threonine residues, deamidation of glutamine or asparagine residues, citrullination and methylation of arginine residues.
Cellular Location:	Myelin membrane. Cytoplasmic side of myelin.
Database Links:	Entrez Gene: 618684?Cow Entrez Gene: 4155?Human Entrez Gene: 17196?Mouse Entrez Gene: 24547?Rat Omim: 159430?Human SwissProt: P02687?Cow SwissProt: P02686?Human SwissProt: P04370?Mouse SwissProt: P02688?Rat Unigene: 551713?Human Unigene: 252063?Mouse Unigene: 392350?Mouse Unigene: 454459?Mouse Unigene: 63285?Rat
Synonyms:	GDB Antibody Golli MBP Antibody Golli MBP; myelin basic protein Antibody Hemopoietic MBP Antibody HMBPR Antibody HUGO Antibody MBP Antibody MBP_CAVPO Antibody MBP_HUMAN Antibody MGC99675 Antibody MLD Antibody Myelin A1 protein Antibody Myelin A1 Protein, basic Antibody Myelin Basic Protein Antibody Myelin Deficient Antibody Myelin membrane encephalitogenic protein Antibody OTTHUMP00000163776 Antibody OTTHUMP00000174387 Antibody OTTHUMP00000174388 Antibody SHI Antibody Shiverer Antibody SP Antibody
Information:	Target information shown above is from the UniProt Consortium.