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Anti-BBC3 Antibody

品牌：Antibodies

货号：

规格：100µl

货期：

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Anti-BBC3 Antibody

商品详情参考文献相关资料

Name:	Anti-BBC3 Antibody See all BBC3 primary antibodies
Description:	Rabbit monoclonal antibody to BBC3.
Applications:	WB, IHC, IF, FC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, ICC: 1:50 - 1:200, IF: 1:50 - 1:200, FC: 1:20 - 1:50.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human BBC3.
Host:	Rabbit
Clonality:	Monoclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Tissue Specificity:	Ubiquitously expressed.
Sequence Similarities:	Belongs to the Bcl-2 family.
Cellular Location:	Mitochondrion. Localized to the mitochondria in order to induce cytochrome c release.