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Anti-Bak (A2) Antibody

品牌：Antibodies

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规格：50µl

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Anti-Bak (A2) Antibody

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Name:	Anti-Bak (A2) Antibody See all Bak primary antibodies
Description:	Rabbit polyclonal antibody to Bak (A2)
Specificity:	Bak (A2) pAb detects endogenous levels of Bak protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to the N-terminal of Human Bak.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 25 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
Tissue Specificity:	Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Sequence Similarities:	Belongs to the Bcl-2 family.
Cellular Location:	Mitochondrion membrane.
Database Links:	Entrez Gene: 578?Human Entrez Gene: 12018?Mouse Entrez Gene: 116502?Rat Omim: 600516?Human SwissProt: Q16611?Human SwissProt: O08734?Mouse Unigene: 485139?Human Unigene: 2443?Mouse Unigene: 14598?Rat
Synonyms:	Apoptosis regulator BAK Antibody Bak Antibody BAK like Antibody Bak NT Antibody Bak1 Antibody BAK_HUMAN Antibody Bcl 2 homologous antagonist/killer Antibody Bcl 2 like 7 protein Antibody Bcl-2 homologous antagonist/killer Antibody Bcl-2-like protein 7 Antibody BCL2 antagonist/killer 1 Antibody Bcl2 like 7 Protein Antibody Bcl2-L-7 Antibody BCL2L7 Antibody CDN1 Antibody Cell death inhibitor 1 Antibody MGC117255 Antibody MGC3887 Antibody NBak Antibody Pro apoptotic protein BAK Antibody
Information:	Target information shown above is from the UniProt Consortium.