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Anti-ADAM12 Antibody

品牌：Antibodies

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规格：100µg

货期：

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Anti-ADAM12 Antibody

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Name:	Anti-ADAM12 Antibody See all ADAM12 primary antibodies
Description:	Goat polyclonal antibody to ADAM12.
Applications:	ELISA, FC, IF, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human ADAM12 (N terminal).
Sequence:	AARPLPVSPARALC
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity).
Tissue Specificity:	Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.
Post-Translational Modification:	The precursor is cleaved by a furin endopeptidase.
Cellular Location:	Cell membrane.
Database Links:	Entrez Gene: 8038?Human Omim: 602714?Human SwissProt: O43184?Human Unigene: 594537?Human
Synonyms:	A disintegrin and metalloproteinase domain 12 Antibody ADA12_HUMAN Antibody ADAM 12 Antibody ADAM metallopeptidase domain 12 Antibody ADAM12 Antibody CAR10 Antibody Disintegrin and metalloproteinase domain-containing protein 12 Antibody MCMP Antibody MCMPMltna Antibody Meltrin alpha Antibody Meltrin-alpha Antibody Metalloprotease disintegrin 12 transmembrane Antibody MLTN Antibody MLTNA Antibody OTTHUMP00000046766 Antibody
Information:	Target information shown above is from the UniProt Consortium.