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Anti-Rho A/B/C Antibody

品牌：Antibodies

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规格：50µl

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Anti-Rho A/B/C Antibody

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Overview

Name:	Anti-Rho A/B/C Antibody See all Rho A primary antibodies
Description:	Rabbit monoclonal antibody to Rho A/B/C
Specificity:	This antibody detects endogenous levels of Rho A/B/C and does not cross-react with related proteins.
Applications:	WB, ICC/IF, IHC, FC
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant antibody.
Host:	Rabbit
Clonality:	Monoclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 24 kDa
Purity:	Protein A affinity purified
Product Form:	Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Target

Function:	Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.
Sequence Similarities:	Belongs to the small GTPase superfamily. Rho family.
Post-Translational Modification:	(Microbial infection) Glycosylated at Tyr-34 by Photorhabdus asymbiotica toxin PAU_02230. Mono-O-GlcNAcylation by PAU_02230 inhibits downstream signaling by an impaired interaction with diverse regulator and effector proteins of Rho and leads to actin disassembly.
Cellular Location:	Cell membrane. Cleavage furrow. Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.
Database Links:	Entrez Gene: 387?Human Entrez Gene: 11848?Mouse Entrez Gene: 117273?Rat Omim: 165390?Human SwissProt: P61586?Human SwissProt: Q9QUI0?Mouse SwissProt: P61589?Rat Unigene: 247077?Human Unigene: 757?Mouse Unigene: 107401?Rat
Synonyms:	Aplysia ras related homolog 12 Antibody ARH12 Antibody ARHA Antibody H 12 Antibody H12 Antibody Oncogene RHO H12 Antibody Ras homolog family member A Antibody Ras homolog gene family member A Antibody Rho A Antibody Rho cDNA clone 12 Antibody RHO H12 Antibody RHO12 Antibody RhoA Antibody RHOA_HUMAN Antibody RHOH12 Antibody Small GTP binding protein Rho A Antibody Transforming protein Rho A Antibody Transforming protein RhoA Antibody
Information:	Target information shown above is from the UniProt Consortium.