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Anti-Nestin Antibody

品牌：Antibodies

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规格：50µl

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Anti-Nestin Antibody

商品详情参考文献相关资料

Name:	Anti-Nestin Antibody See all Nestin primary antibodies
Description:	Mouse monoclonal (4D11) antibody to Nestin.
Applications:	WB, ICC/IF, IHC
Dilutions:	WB: 1:5,000. IF/IHC: 1:500.
Reactivity:	Human, Horse, Cow, Porcine, Chicken, Rat, Mouse
Immunogen:	Amino acids 317-630 of human protein.
Host:	Mouse
Clonality:	Monoclonal
Clone:	4D11
Isotype:	IgG1
Conjugate:	Unconjugated
Purity:	Ascites fluid.
Product Form:	Liquid
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Tissue Specificity:	CNS stem cells.
Sequence Similarities:	Belongs to the intermediate filament family.
Post-Translational Modification:	Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized.
Database Links:	Entrez Gene: 10763?Human Entrez Gene: 18008?Mouse Omim: 600915?Human SwissProt: P48681?Human SwissProt: Q6P5H2?Mouse SwissProt: P21263?Rat Unigene: 527971?Human Unigene: 331129?Mouse Unigene: 9701?Rat
Synonyms:	ESTM 46 Antibody FLJ 21841 Antibody FLJ21841 Antibody Intermediate filament protein Antibody Nbla00170 Antibody nes Antibody Nestin Antibody NEST_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.